Three abstracts on OXC-101 selected for poster presentations at AACR 2023

Oxcia AB (publ) today reports that three abstracts on OXC-101, its clinical candidate for cancer, have been selected for poster presentations at the American Association for Cancer Research (AACRS) Annual meeting held in Orlando, Florida,  14-19[th] April, 2023 . The abstracts concern the clinical safety, further understanding of the broad anti-cancer efficacy and the mechanism of action and will be published in the online Proceedings supplement of the AACR journal Cancer Research.

New pre-clinical study shows that OXC-201 may be a promising treatment for IPF (pulmonary fibrosis)

A new study, “Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis in a murine lung fibrosis model” (freely translated: Pharmacological OGG1 inhibition reduces acute lung injury and lung fibrosis in mice), was published on January 26 in Nature Communications ( https://doi.org/10.1038/s41467-023-36314-5, L. Tanner, A. B. Single, R. K. V. Bhongir , M. Heusel , T. Mohanty, C. A. Q. Karlsson, L. Pan, C-M. Clausson, J. Bergwik , K. Wang, C. K. Andersson, R. M. Oommen, J. S. Erjefält, J. Malmström, O. Wallner, I. Boldogh, T. Helleday, C. Kalderén & A. Egesten) shows that OXC-201 (TH5487) may be a promising treatment for idiopathic pulmonary fibrosis (IPF).

The EIC has awarded Oxcia AB with a EIC transition grant of 2.5 million Euros for development of OXC-201.

Oxcia is very pleased to announce that the EIC (the European Innovation Council) has selected Oxcia’s OXC-201 to receive an EIC Transition grant of 2.5 million Euros. The EIC is Europe’s flagship innovation programme to identify, develop and scale up… Continue reading The EIC has awarded Oxcia AB with a EIC transition grant of 2.5 million Euros for development of OXC-201.

Data show OXC-201 may be a promising treatment for allergic asthma.

A new study, Pharmacological OGG1 inhibition decreases murine allergic airway inflammation, was published 17[th] of October in Respiratory pharmacology, Frontiers in Pharmacology, (DOI 10.3389/fphar.2022.999180, Tanner L, Bergwik J, Bhongir RKV, Pan L, Dong C, Wallner O, Kalderén C, Helleday T, Boldogh I, Adner M and Egesten A) and demonstrates that Oxcia’s potential clinical candidate OXC-201 (TH5487) may be a promising treatment for allergic asthma.